When Cells Take the Wrong Path
Humans and animals are multicellular organisms that rely on complex communication pathways to control the development and function of tissues and organs.
When these signalling pathways operate at the wrong time or place, or when certain proteins are not made properly, cells can behave abnormally. This, in turn, can lead to disease.
Dr. Nina Jones, Canada Research Chair in Eukaryotic Cellular Signalling, is studying how cells transmit their chemical messages and how normal signalling processes can go awry. In particular, she is studying adaptor proteins, which connect one protein to another and facilitate the formation of larger signaling networks.
Jones’ research will provide a better understanding of aspects of development, kidney function, blood vessel formation and nervous system patterning. Her discoveries may ultimately contribute to new treatments for a number of diseases, including cancer and kidney disease.