Lucie Germain

Canada Research Chair in Stem Cells and Tissue Engineering

Tier 1 - 2017-11-01
Université Laval
Canadian Institutes of Health Research

418-990-8255, ext./poste 61696

Research involves

Regenerating organs through tissue engineering and using them to study diseases and develop new medical treatments.

Research relevance

This research will improve survival rates and quality of life for patients who need organ transplants.

Regenerating Organs from Stem Cells in the Laboratory

Organ donation is a topical issue that touches many people afflicted with various diseases. Unfortunately, the need for donor organs is growing and the supply is not keeping up. This is why researchers are turning their attention to generating organs through tissue engineering. Tissue engineering allows the regeneration of tissues and organs in the laboratory thanks to the culture of cells in a three-dimensional environment.  

Dr. Lucie Germain, Canada Research Chair in Stem Cells and Tissue Engineering, is investigating regenerating tissue from human post-natal stem cells. These cells play an important role in regenerating body tissues, and can be used to cultivate organs like skin, corneas, heart valves, cartilage and more.

Germain uses these regenerated tissues as experimental models to study diseases like epidermolysis bullosa or hypertrophic scars as well as to develop new medical treatments.

She and her team have also begun clinical trials of corneal transplants and skin grafts in burn victims. Several patients have already benefitted from treatments developed through tissue engineering.

The unique and original nature of Germain’s research into stem cells and tissue engineering will lead to improvements in care for patients who need transplants or a faster healing process.