Research summary
Researchers have come a long way in their understanding of HIV, as have treatments. However, there are still many things we don’t understand about the immune responses of both people living with HIV and those who remain uninfected.
Dr. Mohammad-Ali Jenabian, Canada Research Chair in Immuno-Virology , is studying the molecular mechanisms involved in these immune responses. He and his research team are assessing the role of regulatory T-cells in accelerated cardiac diseases in addition to T-cell functional immune cross-talk with other types of T-cells. They are also assessing what causes HIV to persist inside the lungs of people living with HIV despite anti-retroviral therapy. Finally, they are evaluating the anti-inflammatory impacts of medical cannabinoids through a randomized clinical trial involving people living with HIV who are receiving anti-retroviral therapy. Ultimately, their findings will contribute to new drug treatments.