Research Summary
Genomic data are transforming how we understand and treat disease. Dr. Lisa Strug, Canada Research Chair in Genome Data Science, is developing advanced data science methods to make use of these data. She is uncovering the genetic factors that influence disease severity and treatment response, with a focus on cystic fibrosis, a genetic disease that causes mucus to build up in the lungs and digestive system.
Strug has already identified key genetic regions that modify how cystic fibrosis affects individuals, paving the way for more personalized care. She and her research team are now using cutting-edge genome sequencing and multi-omic data integration to reveal the mechanisms behind these genetic effects. They are also identifying and prioritizing new drug targets for cystic fibrosis and other lung diseases. This research supports the development of tailored treatments for cystic fibrosis and could lead to insights that are relevant to many other complex diseases.