Research Summary
Metal implants, such as those used in hip and knee replacements, can degrade inside the body. This process releases particles and metal ions that may trigger immune reactions, allergic responses, or toxic effects. Corrosion can occur differently in each patient, influenced by both mechanical wear and chemical processes. As Canada Research Chair in Corrosion Science, Dr. Yolanda Hedberg is investigating how these reactions occur, including the role of manufacturing methods like 3D printing and the interactions between corrosion products and proteins in the body.
She and her research team are also studying how metal nanoparticles—whether produced unintentionally through corrosion or used intentionally in imaging and cancer therapy—affect protein behaviour and immune responses. By uncovering the chemical and physical factors behind implant degradation, their work will inform safer designs and manufacturing practices for biomedical devices, reducing health risks and improving patient outcomes.