Research Summary
Proper brain function depends on constant communication between neurons and blood vessels, which work together to deliver nutrients, remove waste and support cognition. Disruptions in these neurovascular interactions are linked to major brain disorders, including stroke and Alzheimer’s disease. Yet, many of the mechanisms behind this coordination remain poorly understood.
As Canada Research Chair in Neurovascular Interactions, Dr. Ravi Rungta is investigating how brain activity and blood flow interact, how specialized cells called pericytes contribute to vascular function, and how small vessel disease leads to neurovascular dysfunction. He and his research team are combining advanced imaging with cutting-edge neuroscience tools to uncover the inner workings of the brain’s vascular system. By shedding light on how blood vessels and neurons communicate in health and disease, their work could pave the way for better diagnosis and treatment of neurological and neurodegenerative disorders.