Research summary
The overall goal of Dr. Don Sin’s Chair research is to develop biomarkers of disease activity that can be used to target the right therapies to the right patients with chronic obstructive pulmonary disease (COPD), and thereby enable precision medicine. Sin will use “–omics” technology, accompanied by state-of-the-art bioinformatics and statistics, to discover –omics signatures. Sin will use the signatures to predict and subphenotype COPD exacerbations. His will then develop the signatures into blood or sputum tests, for clinical implementation. During this term as Chair, Sin will clinically implement one or two major biomarker tests, as well as create large COPD exacerbation cohorts, research networks and collaborations. These will be a legacy for future COPD researchers in Canada.