Marceline Côté

Canada Research Chair in Molecular Virology and Antiviral Therapeutics

Tier 2 - 2015-08-01
Renewed: 2020-05-01
University of Ottawa
Canadian Institutes of Health Research

613-562-5800, ext./poste 8215

Coming to Canada From

Brigham and Women’s Hospital, Harvard Medical School, Boston, United States

Research involves

Using chemical genomics and genetics to develop antiviral therapies.

Research relevance

This research will support the development of antiviral therapies to fight emerging viruses, such as Ebola, and will help train the next generation of virology experts.

Research summary

Diseases caused by the emerging Ebola, Marburg and Lassa fever viruses are typical “zoonoses.” These viruses persist within reservoir animal species, and occasionally spill over to humans, causing high case-fatality-rate outbreaks. There are currently no antiviral therapies that are effective against these viruses. During her first term as Chair, Dr. Marceline Côté focused on investigating the entry pathways of the Ebola and Marburg viruses, and identifying inhibitors. For her second term, Côté will pursue and expand those studies, towards discovering host factors essential for Lassa fever infection, and developing novel pan-antiviral therapies against these emerging viruses.