Judith Mandl

Canada Research Chair in Immune Cell Dynamics

Tier 2 - 2015-09-01
Renewed: 2021-02-01
McGill University
Canadian Institutes of Health Research


Coming to Canada From

National Institutes of Health, Bethesda, MD, USA

Research involves

Visualising the dynamic behaviour of immune cells using imaging

Research relevance

To understand the processes which orchestrate immune responses in complex tissues and thus develop better therapies targeting the immune system.

Research summary

Immune cells protect us from infection and we deliberately induce their functions when we vaccinate our kids to shield them from a range of what used to be devastating illnesses. Dr. Mandl studies two fascinating properties of immune cells: they are highly motile and can migrate all around the body, and they come in a variety of forms. Their continuous motion and their diversity are both critical to their function. Mandl will investigate how immune cells move through tissue,

immune cell collectives avoid crowding issues, and interactions made during

migration impact the heterogeneity of particular immune cell types.