Aida Ouangraoua

Canada Research Chair in Biological and Computational Complexity

Tier 2 - 2015-12-01
Renewed: 2020-12-01
Université de Sherbrooke
Natural Sciences and Engineering Research Council

819-821-8000, ext. 62014

Coming to Canada From

Inria Lille, France

Research involves

Developing computer models that allow us to decode and compare the different architectures of genome sequences.

Research relevance

This research will shed light on the biological processes behind gene evolution and expression, and may lead to better treatments for certain diseases.

Research summary

Computational genomics refers to the use of computational and statistical analysis to decipher biology from genome sequences and related data. Dr. Aïda Ouangroua, Canada Research Chair in Biological and Computational Complexity, is developing methods to identify functional regions in genomes and discover the evolutionary relationships between functional regions at multiple embedded levels.

She and her research team aim to develop models of multiple RNA families for fast identification of RNA genes. They are also inferring evolutionary relationships between coding genes at the transcripts level and correcting gene trees using gene neighborhood information. Ultimately, their results will help solve some of the key challenges facing modern computational genomics, particularly with regards to scaling up genome annotation to the rapid advances of genome sequencing and allowing more insightful reconstructions of the evolution of genome components.