Robert Todd Alexander

Canada Research Chair in Epithelial Transport Physiology

Tier 2 - 2017-11-01
Renewed: 2021-05-01
University of Alberta
Canadian Institutes of Health Research

Research involves

Understanding how kidneys hold on to important electrolytes during the blood-cleaning process.

Research relevance

This research will help develop new and improved diagnostic tools and treatments for common disorders such as kidney stones, high blood pressure and osteoporosis.

Research summary

In a healthy person, the liver, kidney, intestines and lungs cleanse and detoxify the blood. During this process, the kidney holds onto-and the intestine absorbs-important electrolytes, including sodium, bicarbonate, phosphate and calcium. Dr. Robert Alexander, Canada Research Chair in Epithelial Transport Physiology, aims to better understand how this happens.

Abnormalities in the way some people’s kidneys hold onto electrolytes (or in how the intestine absorbs them) can result in a variety of common disorders, including hypertension, osteoporosis and kidney stones. Alexander and his research team are shedding light on the molecular details of these processes to support the development of new therapies to treat these disorders.