Thousands of Canadians develop diabetes and cardiovascular diseases every year, and some respond better than others to treatments. Dr. Marie-Pierre Dubé, Canada Research Chair in Precision Medicine Data Analysis, is working to figure out why. She and her research team are trying to identify and validate new drug targets and identify subgroups of patients who respond better to medications. Their goal is to discover new precision medicine solutions to treat cardiovascular diseases and diabetes.
To accomplish this, Dube is building on her world-recognized expertise in statistical genetics and pharmacogenomics (the study of the relationship between individual genetic variation and drug response). She and her team are using large genomic datasets to perform analyses using traditional statistics, artificial intelligence and causal inference models. They hope to be able to draw conclusions from their data analyses that will support developments in personalized medicine.