Research summary
As Canada Research Chair in Tissue Remodelling and Plasticity Throughout the Lifespan, Dr. Val Andrew Fajardo is looking for ways to promote physiological remodelling to help people live better and longer lives. In particular, Fajardo and his research team are focusing on inhibiting glycogen synthase kinase 3 (a protein implicated in several diseases) and promoting the function of a calcium pump in muscle called SERCA. His lab focuses on these targets using genetic and pharmacological approaches with the hopes of influencing adaptive changes in muscle that can be useful in the fight against obesity, aging and disease, as well as for spaceflight.