Research Summary
Osteoarthritis affects more than four million Canadians, causing chronic joint pain, loss of mobility, and reduced quality of life—and no approved therapies exist to slow or stop the disease. Dr. Mohit Kapoor, Canada Research Chair in the Mechanisms of Joint Degeneration, is tackling this problem by studying how osteoarthritis damages joints, finding reliable ways to detect it earlier, and developing new treatments to slow or prevent joint destruction.
Kapoor has already created one of the world’s largest osteoarthritis biobanks. Using cutting-edge tools to study joint tissues and track disease changes, he and his research team are now building a detailed “map” of the cells involved, testing a new approach to reduce harmful tissue scarring, and advancing a promising therapy from the lab toward human trials. Ultimately, they aim to deliver the first treatment that can truly change the course of the disease.