Dr. Eric Arts’ lab believes that curing HIV/AIDS is an achievable goal. The laboratory has focused on understanding how HIV-1 virulence and evolution affects disease progression, transmission and spread. Using samples from HIV-infected cohorts from around the world, the team is examining if HIV-1 has evolved into different subtypes. For example, it has found the predominant subtype C is less virulent and causes slower disease but is more easily transmitted. It also responds better to antiretroviral treatment. Knowing the virulence of the different HIV subtypes could dramatically impact how the virus is treated with drugs. These studies also help forecast the future HIV epidemic, design vaccines and, finally, establish how, when and with what drugs to treat patients infected with diverse HIV-1 strains.